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If you use this service, could you please send us a mail to npsang@ibcp.fr with details about your usage of the NPSA service (tools used, frequency, type of sequence, ..) ? Could you explain what makes this service unique for you ? Could you please add information about your country and your laboratory ? Thanks

When in a NPS@ output you see the NPSA link, it allows you to work with a sequence and apply NPS@ methods on it.

What can you do then ?
You can :

• View it it in MPSA/ ANTHEPROT
• Do a homology search. The sequence will be the query one.
• Scan the sequence against PROSITE database.
• Search the sequence for one or several pattern (PATTINPROT ).
• Make a consensus secondary prediction (12 secondary structure prediction methods available).
• Do primary analysis (amphipaseek, physico-chemical profiles, coiled coils prediction, helix-turn-helix detection, amino-acid composition and sequence coloring).

NPS@ three-dimensional links
When the sequence comes from a 3D database, more links are available :

• A link on PDB file summary at IGH (France), RCSB (USA) or EBI (UK).
• Secondary structure can be deduced from 3D by DSSP or P-SEA programs.
• Full PDB file can be retrieve (at NPS@).
• You can view the structure in RASMOL or ANTHEPROT.
  The MIME type to use is chemical/x-pdb for RASMOL and chemical/x-antheprot for ANTHEPROT.
• A link on 3DEE database.
• A link on CATH database.
• A link on FSSP database.
• A link on SCOP database.
• A link on MOLMOV database.