[Abstract] [NPS@ help] [Original server]
Paste a multiple protein alignment in clustalw format below : help
Alignment boundaries : If new alignment boundaries, keep sequences with at least residues in alignment region.
Profile HMM construction options : Alignment mode : Global (-g) Domain Local (-s) Multi-hit local (-f) Weighting mode : BLOSUM filtering algo (--wblosum) Gerstein/Sonnhammer/Chothia algo (--wgsc) Krogh/Mitchison max entropy algo (--wme) Henikoff position based algo (--wpb) Sibbald/Argos Voronoi algo (--wvoronoi) No sequence weighting (--wnone) If blosum weighting mode, you can choose percent identity (--idlevel, fraction from 0 to 1): Switching behavior (weighting mode) (--pbswitch, positive int) :
Profile HMM calibration options : Number of synthetic sequences (preferably upper than 1000) (--num, positive int) : Gaussian mean (--mean, positive real) : Gaussian standard deviation (--sd, positive real) :